Endocrine Abstracts

Aim: To estimate the efficacy of structured lifestyle modification program on clinical and metabolic status in overweight/obese patients with type 2 diabetes (T2DM).Materials and methods: The program was implemented in 2 centers (Moscow, Kazan) and 130 participants were recruited (100-active group, 30-control group). The patients’ characteristics in active group: mean age was 54.6±10.2 years, diabetes duration 6.6±5.6 years, BMI 34.4±...

Aim: To study prevalence of foot complications in patients on dialysis therapy and evaluate the role the haemodynamic changes during dialysis procedure in development of foot problems.Methods: 109 dialysis patients, mean age 49 years. 60 of them had diabetes mellitus (DM): 29 on haemodialysis (HD), 31 on peritoneal dialysis (PD). Non-diabetic patients (NDM): 24 HD, 25 PD.Vascular status: doppler, photoplethysmography. Polyneuropath...

Background: Werner syndrome is a rare autosomal recessive disease caused by a mutation of the DNA helicase gene (WRN), characterized by the premature onset of multiple age-related disorders.Objective: To describe unusual multiple endocrine and metabolic disorders in three unrelated clinical cases of Werner syndrome.Methods: Three patients with obvious clinical features of premature ageing were referred to an endocrinologist due to ...